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The Fanconi Anemia Pathway in Cancer

Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure (BMF), congenital defects, inability to repair DNA interstrand cross-links (ICLs), and cancer predisposition. FA presents two seemingly opposite characteristics: (a) massive cell death of the hematopoietic stem an...

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書目詳細資料
發表在:Annu Rev Cancer Biol
Main Authors: Niraj, Joshi, Färkkilä, Anniina, D’Andrea, Alan D.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417835/
https://ncbi.nlm.nih.gov/pubmed/30882047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-cancerbio-030617-050422
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