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The Fanconi Anemia Pathway in Cancer
Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure (BMF), congenital defects, inability to repair DNA interstrand cross-links (ICLs), and cancer predisposition. FA presents two seemingly opposite characteristics: (a) massive cell death of the hematopoietic stem an...
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| Publicado no: | Annu Rev Cancer Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6417835/ https://ncbi.nlm.nih.gov/pubmed/30882047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-cancerbio-030617-050422 |
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