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Expanded roles of the Fanconi anemia pathway in preserving genomic stability

Studying rare human genetic diseases often leads to a better understanding of normal cellular functions. Fanconi anemia (FA), for example, has elucidated a novel DNA repair mechanism required for maintaining genomic stability and preventing cancer. The FA pathway, an essential tumor-suppressive path...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kee, Younghoon, D'Andrea, Alan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922498/
https://ncbi.nlm.nih.gov/pubmed/20713514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1955310
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