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Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis

The 13 Fanconi anemia (FA) proteins cooperate in a common DNA repair pathway. Eight of these proteins are assembled into a multisubunit E3 ligase called the FA core complex. During S phase, the FA core complex is loaded by the FANCM protein into chromatin where it monoubiquitinates its substrates. I...

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Detalhes bibliográficos
Main Authors: Kee, Younghoon, Kim, Jung Min, D'Andrea, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658523/
https://ncbi.nlm.nih.gov/pubmed/19270156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1761309
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