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How the Fanconi Anemia pathway guards the genome

Fanconi Anemia (FA) is an inherited genomic instability disorder, caused by mutations in genes regulating replication-dependent removal of interstrand DNA crosslinks. The Fanconi Anemia pathway is thought to coordinate a complex mechanism that enlists elements of three classic DNA repair pathways, n...

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Detalhes bibliográficos
Main Authors: Moldovan, George-Lucian, D’Andrea, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830711/
https://ncbi.nlm.nih.gov/pubmed/19686080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-102108-134222
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