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Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

Age-associated neurological diseases represent a profound challenge in biomedical research as we are still struggling to understand the interface between the aging process and the manifestation of disease. Various pathologies in the elderly do not directly result from genetic mutations, toxins, or i...

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Detalhes bibliográficos
Publicado no:Annu Rev Genet
Main Authors: Mertens, Jerome, Reid, Dylan, Lau, Shong, Kim, Yongsung, Gage, Fred H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415910/
https://ncbi.nlm.nih.gov/pubmed/30208291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-120417-031534
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