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Precision Modulation of Neurodegenerative Disease-Related Gene Expression in Human iPSC-Derived Neurons

The ability to reprogram adult somatic cells into induced pluripotent stem cells (iPSCs) and the subsequent development of protocols for their differentiation into disease-relevant cell types have enabled in-depth molecular analyses of multiple disease states as hitherto impossible. Neurons differen...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Heman-Ackah, Sabrina Mahalia, Bassett, Andrew Roger, Wood, Matthew John Andrew
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920027/
https://ncbi.nlm.nih.gov/pubmed/27341390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28420
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