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Molecular and functional variation in iPSC-derived sensory neurons

Induced pluripotent stem cells (iPSCs), and cells derived from them, have become key tools to model biological processes, particularly in cell types that are difficult to access from living donors. We present the first map of regulatory variants in iPSC-derived neurons, based on 123 differentiations...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Schwartzentruber, Jeremy, Foskolou, Stefanie, Kilpinen, Helena, Rodrigues, Julia, Alasoo, Kaur, Knights, Andrew, Patel, Minal, Goncalves, Angela, Ferreira, Rita, Benn, Caroline Louise, Wilbrey, Anna, Bictash, Magda, Impey, Emma, Cao, Lishuang, Lainez, Sergio, Loucif, Alexandre Julien, Whiting, Paul John, Gutteridge, Alex, Gaffney, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742539/
https://ncbi.nlm.nih.gov/pubmed/29229984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-017-0005-8
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