Molecular and functional variation in iPSC-derived sensory neurons

Induced pluripotent stem cells (iPSCs), and cells derived from them, have become key tools to model biological processes, particularly in cell types that are difficult to access from living donors. We present the first map of regulatory variants in iPSC-derived neurons, based on 123 differentiations...

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Veröffentlicht in:Nat Genet
Hauptverfasser: Schwartzentruber, Jeremy, Foskolou, Stefanie, Kilpinen, Helena, Rodrigues, Julia, Alasoo, Kaur, Knights, Andrew, Patel, Minal, Goncalves, Angela, Ferreira, Rita, Benn, Caroline Louise, Wilbrey, Anna, Bictash, Magda, Impey, Emma, Cao, Lishuang, Lainez, Sergio, Loucif, Alexandre Julien, Whiting, Paul John, Gutteridge, Alex, Gaffney, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742539/
https://ncbi.nlm.nih.gov/pubmed/29229984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-017-0005-8
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