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Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

Age-associated neurological diseases represent a profound challenge in biomedical research as we are still struggling to understand the interface between the aging process and the manifestation of disease. Various pathologies in the elderly do not directly result from genetic mutations, toxins, or i...

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Bibliografiske detaljer
Udgivet i:Annu Rev Genet
Main Authors: Mertens, Jerome, Reid, Dylan, Lau, Shong, Kim, Yongsung, Gage, Fred H.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415910/
https://ncbi.nlm.nih.gov/pubmed/30208291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-120417-031534
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