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Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

Age-associated neurological diseases represent a profound challenge in biomedical research as we are still struggling to understand the interface between the aging process and the manifestation of disease. Various pathologies in the elderly do not directly result from genetic mutations, toxins, or i...

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Bibliografski detalji
Izdano u:Annu Rev Genet
Glavni autori: Mertens, Jerome, Reid, Dylan, Lau, Shong, Kim, Yongsung, Gage, Fred H.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415910/
https://ncbi.nlm.nih.gov/pubmed/30208291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-120417-031534
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