IL-27 targets Foxp3(+) Tregs to mediate antiinflammatory functions during experimental allergic airway inflammation

Foxp3(+) CD4 Tregs are central regulators of inflammation, including allergic inflammation in the lung. There is increasing evidence that inflammatory factors undermine adequate Treg functions and homeostasis, resulting in prolonged and exacerbated inflammation. Therefore, identifying the factors is...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Nguyen, Quang Tam, Jang, Eunjung, Le, Hongnga T., Kim, Sohee, Kim, Dongkyun, Dvorina, Nina, Aronica, Mark A., Baldwin, William M., Asosingh, Kewal, Comhair, Suzy, Min, Booki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413774/
https://ncbi.nlm.nih.gov/pubmed/30674714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123216
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