Site-Specific Cleavage of RNAs Derived from the PIM1 3′-UTR by a Metal-Free Artificial Ribonuclease

Oligonucleotide conjugates of tris(2-aminobenzimidazole) have been reported previously to cleave complementary RNA strands with high levels of sequence and site specificity. The RNA substrates used in these studies were oligonucleotides not longer than 29-mers. Here we show that ~150–400-mer model t...

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I publikationen:Molecules
Huvudupphovsmän: Zellmann, Felix, Thomas, Laura, Scheffer, Ute, Hartmann, Roland K., Göbel, Michael W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412833/
https://ncbi.nlm.nih.gov/pubmed/30813393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24040807
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