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Transcriptome-Wide Cleavage Site Mapping on Cellular mRNAs Reveals Features Underlying Sequence-Specific Cleavage by the Viral Ribonuclease SOX

Many viruses express factors that reduce host gene expression through widespread degradation of cellular mRNA. An example of this class of proteins is the mRNA-targeting endoribonuclease SOX from the gamma-herpesvirus Kaposi’s sarcoma-associated herpesvirus (KSHV). Previous studies indicated that cl...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gaglia, Marta Maria, Rycroft, Chris H., Glaunsinger, Britt A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672902/
https://ncbi.nlm.nih.gov/pubmed/26646420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005305
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