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Transcriptome-Wide Cleavage Site Mapping on Cellular mRNAs Reveals Features Underlying Sequence-Specific Cleavage by the Viral Ribonuclease SOX

Many viruses express factors that reduce host gene expression through widespread degradation of cellular mRNA. An example of this class of proteins is the mRNA-targeting endoribonuclease SOX from the gamma-herpesvirus Kaposi’s sarcoma-associated herpesvirus (KSHV). Previous studies indicated that cl...

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Vydáno v:PLoS Pathog
Hlavní autoři: Gaglia, Marta Maria, Rycroft, Chris H., Glaunsinger, Britt A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672902/
https://ncbi.nlm.nih.gov/pubmed/26646420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005305
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