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Ribonuclease L and metal-ion–independent endoribonuclease cleavage sites in host and viral RNAs

Ribonuclease L (RNase L) is a metal-ion–independent endoribonuclease associated with antiviral and antibacterial defense, cancer and lifespan. Despite the biological significance of RNase L, the RNAs cleaved by this enzyme are poorly defined. In this study, we used deep sequencing methods to reveal...

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Bibliografiska uppgifter
Huvudupphovsmän: Cooper, Daphne A., Jha, Babal K., Silverman, Robert H., Hesselberth, Jay R., Barton, David J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
RNA
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005677/
https://ncbi.nlm.nih.gov/pubmed/24500209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku118
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