Á lódáil...

The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency

USP37 is a deubiquitinase (DUB) with roles in the regulation of DNA damage repair and the cohesion of sister chromatids during mitosis. USP37 contains a unique insert of three ubiquitin interacting motifs (UIMs) within its catalytic DUB domain. We investigated the role of the three UIMs in the abili...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Sci Rep
Main Authors: Manczyk, Noah, Veggiani, Gianluca, Teyra, Joan, Strilchuk, Amy W., Sidhu, Sachdev S., Sicheri, Frank
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412040/
https://ncbi.nlm.nih.gov/pubmed/30858488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40815-z
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!