Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer

INTRODUCTION: Colorectal cancers (CRCs) deficient in the DNA mismatch repair protein MutL homolog 1 (MLH1) display distinct clinicopathological features and require a different therapeutic approach compared to CRCs with MLH1 proficiency. However, the molecular basis of this fundamental difference re...

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Udgivet i:PLoS One
Main Authors: Ackermann, Anne, Schrecker, Christopher, Bon, Dimitra, Friedrichs, Nicolaus, Bankov, Katrin, Wild, Peter, Plotz, Guido, Zeuzem, Stefan, Herrmann, Eva, Hansmann, Martin-Leo, Brieger, Angela
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411122/
https://ncbi.nlm.nih.gov/pubmed/30856214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213411
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