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Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer
INTRODUCTION: Colorectal cancers (CRCs) deficient in the DNA mismatch repair protein MutL homolog 1 (MLH1) display distinct clinicopathological features and require a different therapeutic approach compared to CRCs with MLH1 proficiency. However, the molecular basis of this fundamental difference re...
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| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411122/ https://ncbi.nlm.nih.gov/pubmed/30856214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213411 |
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