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N-terminus of hMLH1 confers interaction of hMutLα and hMutLβ with hMutSα

Mismatch repair is a highly conserved system that ensures replication fidelity by repairing mispairs after DNA synthesis. In humans, the two protein heterodimers hMutSα (hMSH2-hMSH6) and hMutLα (hMLH1-hPMS2) constitute the centre of the repair reaction. After recognising a DNA replication error, hMu...

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Detalhes bibliográficos
Main Authors: Plotz, Guido, Raedle, Jochen, Brieger, Angela, Trojan, Jörg, Zeuzem, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162253/
https://ncbi.nlm.nih.gov/pubmed/12799449
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