Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation

Podocalyxin (Podxl) is broadly expressed on the luminal face of most blood vessels in adult vertebrates, yet its function on these cells is poorly defined. In the present study, we identified specific functions for Podxl in maintaining endothelial barrier function. Using electrical cell substrate im...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Cait, Jessica, Hughes, Michael R., Zeglinski, Matthew R., Chan, Allen W., Osterhof, Sabrina, Scott, R. Wilder, Canals Hernaez, Diana, Cait, Alissa, Vogl, A. Wayne, Bernatchez, Pascal, Underhill, T. Michael, Granville, David J., Murphy, Timothy H., Roskelley, Calvin D., McNagny, Kelly M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410846/
https://ncbi.nlm.nih.gov/pubmed/30787191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814766116
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