Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation

Podocalyxin (Podxl) is broadly expressed on the luminal face of most blood vessels in adult vertebrates, yet its function on these cells is poorly defined. In the present study, we identified specific functions for Podxl in maintaining endothelial barrier function. Using electrical cell substrate im...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cait, Jessica, Hughes, Michael R., Zeglinski, Matthew R., Chan, Allen W., Osterhof, Sabrina, Scott, R. Wilder, Canals Hernaez, Diana, Cait, Alissa, Vogl, A. Wayne, Bernatchez, Pascal, Underhill, T. Michael, Granville, David J., Murphy, Timothy H., Roskelley, Calvin D., McNagny, Kelly M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410846/
https://ncbi.nlm.nih.gov/pubmed/30787191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814766116
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