Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease

Dominant and recessive mutations in podocalyxin (PODXL) are associated with human kidney disease. Interestingly, some PODXL mutations manifest as anuria while others are associated with proteinuric kidney disease. PODXL heterozygosity is associated with adult-onset kidney disease and podocalyxin she...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Refaeli, Ido, Hughes, Michael R., Wong, Alvin Ka-Wai, Bissonnette, Mei Lin Z., Roskelley, Calvin D., Wayne Vogl, A., Barbour, Sean J., Freedman, Benjamin S., McNagny, Kelly M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286918/
https://ncbi.nlm.nih.gov/pubmed/32523052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64907-3
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