Gene-edited human kidney organoids reveal mechanisms of disease in podocyte development

A critical event during kidney organogenesis is the differentiation of podocytes, specialized epithelial cells that filter blood plasma to form urine. Podocytes derived from human pluripotent stem cells (hPSC-podocytes) have recently been generated in nephron-like kidney organoids, but the developme...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kim, Yong Kyun, Refaeli, Ido, Brooks, Craig R., Jing, Peifeng, Gulieva, Ramila E., Hughes, Michael R., Cruz, Nelly M., Liu, Yannan, Churchill, Angela J., Wang, Yuliang, Fu, Hongxia, Pippin, Jeffrey W., Lin, Lih Y., Shankland, Stuart J., Vogl, A. Wayne, McNagny, Kelly M., Freedman, Benjamin S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742857/
https://ncbi.nlm.nih.gov/pubmed/28905451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2707
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