Mitochondria: Regulators of Cell Death and Survival

Por Granville, David J., Gottlieb, Roberta A.
Publicado no ScientificWorldJournal (2002)

Granzyme B Releases Vascular Endothelial Growth Factor from Extracellular Matrix and Induces Vascular Permeability

Por Hendel, Alon, Hsu, Ivy, Granville, David J.
Publicado em 2014

Perforin Mediates Endothelial Cell Death and Resultant Transplant Vascular Disease in Cardiac Allografts

Por Choy, Jonathan C., Kerjner, Alexandra, Wong, Brian W., McManus, Bruce M., Granville, David J.
Publicado em 2004

Granzyme K Activates Protease-Activated Receptor-1

Por Cooper, Dawn M., Pechkovsky, Dmitri V., Hackett, Tillie L., Knight, Darryl A., Granville, David J.
Publicado em 2011

Perforin and Granzyme B Have Separate and Distinct Roles during Atherosclerotic Plaque Development in Apolipoprotein E Knockout Mice

Por Hiebert, Paul R., Boivin, Wendy A., Zhao, Hongyan, McManus, Bruce M., Granville, David J.
Publicado em 2013

Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation

Por Parkinson, Leigh G, Toro, Ana, Zhao, Hongyan, Brown, Keddie, Tebbutt, Scott J, Granville, David J
Publicado no Aging Cell (2015)

Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice

Por Wang, Eddy, Chong, Katy, Yu, Mei, Akhoundsadegh, Noushin, Granville, David J., Shapiro, Jerry, McElwee, Kevin J.
Publicado em 2013

Lipids, adiposity and tendinopathy: is there a mechanistic link? Critical review

Por Scott, Alex, Zwerver, Johannes, Grewal, Navi, de Sa, Agnetha, Alktebi, Thuraya, Granville, David J, Hart, David A
Publicado no Br J Sports Med (2015)

Granzyme B Cleaves Decorin, Biglycan and Soluble Betaglycan, Releasing Active Transforming Growth Factor-β1

Por Boivin, Wendy A., Shackleford, Marlo, Vanden Hoek, Amanda, Zhao, Hongyan, Hackett, Tillie L., Knight, Darryl A., Granville, David J.
Publicado em 2012

Correction: Granzyme B Cleaves Decorin, Biglycan and Soluble Betaglycan, Releasing Active Transforming Growth Factor-β1

Por Boivin, Wendy A., Shackleford, Marlo, Vanden Hoek, Amanda, Zhao, Hongyan, Hackett, Tillie L., Knight, Darryl A., Granville, David J.
Publicado em 2012

Release of Cytochrome c, Bax Migration, Bid Cleavage, and Activation of Caspases 2, 3, 6, 7, 8, and 9 during Endothelial Cell Apoptosis

Por Granville, David J., Shaw, Janet R., Leong, Simon, Carthy, Christopher M., Margaron, Philippe, Hunt, David W., McManus, Bruce M.
Publicado em 1999

Accumulation of Oxidized LDL in the Tendon Tissues of C57BL/6 or Apolipoprotein E Knock-Out Mice That Consume a High Fat Diet: Potential Impact on Tendon Health

Por Grewal, Navdeep, Thornton, Gail M., Behzad, Hayedeh, Sharma, Aishwariya, Lu, Alex, Zhang, Peng, Reid, W. Darlene, Granville, David J., Scott, Alex
Publicado no PLoS One (2014)

Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors

Por Granville, David J., Tashakkor, Babak, Takeuchi, Cindy, Gustafsson, Åsa B., Huang, Chengqun, Sayen, M. Richard, Wentworth, Paul, Yeager, Mark, Gottlieb, Roberta A.
Publicado em 2004

Caspase Activation and Specific Cleavage of Substrates after Coxsackievirus B3-Induced Cytopathic Effect in HeLa Cells

Por Carthy, Christopher M., Granville, David J., Watson, Kathleen A., Anderson, Daniel R., Wilson, Janet E., Yang, Decheng, Hunt, David W. C., McManus, Bruce M.
Publicado em 1998

Mitochondrial Release of Apoptosis-Inducing Factor and Cytochrome c During Smooth Muscle Cell Apoptosis

Por Granville, David J., Cassidy, Brighid A., Ruehlmann, Dietrich O., Choy, Jonathan C., Brenner, Catherine, Kroemer, Guido, van Breemen, Cornelis, Margaron, Philippe, Hunt, David W., McManus, Bruce M.
Publicado em 2001

Perforin-Independent Extracellular Granzyme B Activity Contributes to Abdominal Aortic Aneurysm

Por Chamberlain, Ciara M., Ang, Lisa S., Boivin, Wendy A., Cooper, Dawn M., Williams, Sarah J., Zhao, Hongyan, Hendel, Alon, Folkesson, Maggie, Swedenborg, Jesper, Allard, Michael F., McManus, Bruce M., Granville, David J.
Publicado em 2010

Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction

Por Russo, Valerio, Klein, Theo, Lim, Darielle J., Solis, Nestor, Machado, Yoan, Hiroyasu, Sho, Nabai, Layla, Shen, Yue, Zeglinski, Matthew R., Zhao, Hongyan, Oram, Cameron P., Lennox, Peter A., Van Laeken, Nancy, Carr, Nick J., Crawford, Richard I., Franzke, Claus-Werner, Overall, Christopher M., Granville, David J.
Publicado no Sci Rep (2018)

Recombinant Decorin Fusion Protein Attenuates Murine Abdominal Aortic Aneurysm Formation and Rupture

Por Shen, Yue, Russo, Valerio, Zeglinski, Matthew R., Sellers, Stephanie L., Wu, Zhengguo, Oram, Cameron, Santacruz, Stephanie, Merkulova, Yulia, Turner, Christopher, Tauh, Keerit, Zhao, Hongyan, Bozin, Tatjana, Bohunek, Lubos, Zeng, Haishan, Seidman, Michael A., Bleackley, R. Chris, McManus, Bruce M., Ruoslahti, Erkki, Järvinen, Tero A. H., Granville, David J.
Publicado no Sci Rep (2017)

Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing

Por Shen, Yue, Zeglinski, Matthew R., Turner, Christopher T., Raithatha, Sheetal A., Wu, Zhenguo, Russo, Valerio, Oram, Cameron, Hiroyasu, Sho, Nabai, Layla, Zhao, Hongyan, Bozin, Tatjana, Westendorf, Kathryn, Kopko, Irina, Huang, Rachel, Arns, Steve, Tan, Jason, Zeng, Haishan, Boey, Anthony, Liggins, Richard, Jaquith, James, Cameron, Dale R., Papp, Anthony, Granville, David J.
Publicado no Exp Mol Med (2018)