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Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing
Granzyme B (GzmB) is a serine protease that has long been thought to function exclusively in lymphocyte-mediated apoptosis. In recent years, this paradigm has been revisited due to the recognition that GzmB accumulates in the extracellular milieu in many autoimmune and chronic inflammatory disorders...
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Publicado no: | Exp Mol Med |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5976625/ https://ncbi.nlm.nih.gov/pubmed/29849046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0095-0 |
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