Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy

INTRODUCTION: Podocalyxin (gene name PODXL) is a CD34-related sialomucin implicated in the regulation of cell adhesion, migration and polarity. Upregulated expression of podocalyxin is linked to poor patient survival in epithelial cancers. However, it is not known if podocalyxin has a functional rol...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Snyder, Kimberly A, Hughes, Michael R, Hedberg, Bradley, Brandon, Jill, Hernaez, Diana Canals, Bergqvist, Peter, Cruz, Frederic, Po, Kelvin, Graves, Marcia L, Turvey, Michelle E, Nielsen, Julie S, Wilkins, John A, McColl, Shaun R, Babcook, John S, Roskelley, Calvin D, McNagny, Kelly M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423095/
https://ncbi.nlm.nih.gov/pubmed/25887862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0562-7
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