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Atomistic-level study of the interactions between hIAPP protofibrils and membranes: Influence of pH and lipid composition
The pathology of type 2 diabetes mellitus is associated with the aggregation of human islet amyloid polypeptide (hIAPP) and aggregation-mediated membrane disruption. The interactions of hIAPP aggregates with lipid membrane, as well as the effects of pH and lipid composition at the atomic level, rema...
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| Publicado en: | Biochim Biophys Acta Biomembr |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6408309/ https://ncbi.nlm.nih.gov/pubmed/29428499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2018.02.005 |
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