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Adsorption and Orientation of Human Islet Amyloid Polypeptide (hIAPP) Monomer at Anionic Lipid Bilayers: Implications for Membrane-Mediated Aggregation

Protein misfolding and aggregation cause serious degenerative diseases, such as Alzheimer’s and type II diabetes. Human islet amyloid polypeptide (hIAPP) is the major component of amyloid deposits found in the pancreas of type II diabetic patients. Increasing evidence suggests that β-cell death is r...

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Detalhes bibliográficos
Main Authors: Jia, Yan, Qian, Zhenyu, Zhang, Yun, Wei, Guanghong
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634446/
https://ncbi.nlm.nih.gov/pubmed/23519103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14036241
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