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Amphiphilic Adsorption of Human Islet Amyloid Polypeptide Aggregates to Lipid/Aqueous Interfaces

Many amyloid proteins misfold into β-sheet aggregates upon interacting with biomembranes at the onset of diseases, such as Parkinson’s disease and type II diabetes. The molecular mechanisms triggering aggregation depend on the orientation of β-sheets at the cell membranes. However, understanding how...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xiao, Dequan, Fu, Li, Liu, Jian, Batista, Victor S., Yan, Elsa C. Y.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350761/
https://ncbi.nlm.nih.gov/pubmed/22210153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.035
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