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Genetic association and transcriptome integration identify contributing genes and tissues at cystic fibrosis modifier loci
Cystic Fibrosis (CF) exhibits morbidity in several organs, including progressive lung disease in all patients and intestinal obstruction at birth (meconium ileus) in ~15%. Individuals with the same causal CFTR mutations show variable disease presentation which is partly attributed to modifier genes....
Kaydedildi:
| Yayımlandı: | PLoS Genet |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6407791/ https://ncbi.nlm.nih.gov/pubmed/30807572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008007 |
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