Dickkopf-1 (DKK1) promotes tumor growth via Akt-phosphorylation and independently of Wnt-axis in Barrett’s associated esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) is still associated with poor prognosis, despite modern multi-modal therapies. New molecular markers, which control cell cycle and promote lymph node metastases or tumor growth, may introduce novel target therapies. Dickkopf-1 (DKK1) is a secreted glycoprotein that bl...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Lyros, Orestis, Lamprecht, Ann-Kristin, Nie, Linghui, Thieme, René, Götzel, Katharina, Gasparri, Mario, Haasler, George, Rafiee, Parvaneh, Shaker, Reza, Gockel, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405970/
https://ncbi.nlm.nih.gov/pubmed/30906632
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