Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett’s Esophagus: Regulation via Dickkopf-1()()

INTRODUCTION: Wnt/β-catenin signaling activation has been reported only during the late steps of Barrett’s esophagus (BE) neoplastic progression, but not in BE metaplasia, based on the absence of nuclear β-catenin. However, β-catenin transcriptional activity has been recorded in absence of robust nu...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Lyros, Orestis, Rafiee, Parvaneh, Nie, Linghui, Medda, Rituparna, Jovanovic, Nebojsa, Otterson, Mary F., Behmaram, Behnaz, Gockel, Ιnes, Mackinnon, Alexander, Shaker, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547437/
https://ncbi.nlm.nih.gov/pubmed/26297437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.07.006
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