The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces

Osteoblast differentiation on tissue culture polystyrene (TCPS) requires Wnt/beta-catenin signaling, regulating modulators of the Wnt pathway like Dickkopf-1 (Dkk1) and Dkk2. Osteoblast differentiation is increased on microstructured titanium (Ti) surfaces compared to TCPS; therefore, we hypothesize...

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Bibliographic Details
Main Authors: Olivares-Navarrete, Rene, Hyzy, Sharon, Wieland, Marco, Boyan, Barbara D., Schwartz, Zvi
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618462/
https://ncbi.nlm.nih.gov/pubmed/20004015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.11.071
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