Direct and Indirect Effects of Microstructured Titanium Substrates on the Induction of Mesenchymal Stem Cell Differentiation towards the Osteoblast Lineage

Microstructured and high surface energy titanium substrates increase osseointegration in vivo. In vitro, osteoblast differentiation is increased, but effects of the surface directly on multipotent mesenchymal stem cells (MSCs) and consequences for MSCs in the peri-implant environment are not known....

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Main Authors: Olivares-Navarrete, Rene, Hyzy, Sharon, Hutton, Daphne, Erdman, Christopher, Wieland, Marco, Boyan, Barbara D., Schwartz, Zvi
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821717/
https://ncbi.nlm.nih.gov/pubmed/20053436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.12.029
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