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Direct and Indirect Effects of Microstructured Titanium Substrates on the Induction of Mesenchymal Stem Cell Differentiation towards the Osteoblast Lineage

Microstructured and high surface energy titanium substrates increase osseointegration in vivo. In vitro, osteoblast differentiation is increased, but effects of the surface directly on multipotent mesenchymal stem cells (MSCs) and consequences for MSCs in the peri-implant environment are not known....

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Autors principals: Olivares-Navarrete, Rene, Hyzy, Sharon, Hutton, Daphne, Erdman, Christopher, Wieland, Marco, Boyan, Barbara D., Schwartz, Zvi
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821717/
https://ncbi.nlm.nih.gov/pubmed/20053436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.12.029
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