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In-depth characterization of the Wnt-signaling/β-catenin pathway in an in vitro model of Barrett’s sequence

BACKGROUND: An altered Wnt-signaling activation has been reported during Barrett’s esophagus progression, but with rarely detected mutations in APC and β-catenin (CTNNB1) genes. METHODS: In this study, a robust in-depth expression pattern analysis of frizzled receptors, co-receptors, the Wnt-ligands...

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Dades bibliogràfiques
Publicat a:BMC Gastroenterol
Autors principals: Götzel, Katharina, Chemnitzer, Olga, Maurer, Luisa, Dietrich, Arne, Eichfeld, Uwe, Lyros, Orestis, Moulla, Yusef, Niebisch, Stefan, Mehdorn, Matthias, Jansen-Winkeln, Boris, Vieth, Michael, Hoffmeister, Albrecht, Gockel, Ines, Thieme, René
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404335/
https://ncbi.nlm.nih.gov/pubmed/30841855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-019-0957-5
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