Nrf2/Keap1-Pathway Activation and Reduced Susceptibility to Chemotherapy Treatment by Acidification in Esophageal Adenocarcinoma Cells

SIMPLE SUMMARY: Inflammation caused by acidic reflux contributes to disease progression in Barrett’s esophagus. Little is known, whether esophageal cancer cells are influenced by acidic reflux and whether reflux influences cancer cell physiology, targeting the Nrf2/Kepa1- and the NFκB-pathway. The u...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Storz, Lucie, Walther, Philipp, Chemnitzer, Olga, Lyros, Orestis, Niebisch, Stefan, Mehdorn, Matthias, Jansen-Winkeln, Boris, Moulla, Yusef, Büch, Thomas, Gockel, Ines, Thieme, René
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200109/
https://ncbi.nlm.nih.gov/pubmed/34199909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112806
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