Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

BACKGROUND: Niacin is a broad‐spectrum lipid‐modulating drug, but its mechanism of action is unclear. Genome‐wide association studies have identified multiple loci associated with blood lipid levels and lipoprotein (a). It is unknown whether these loci modulate response to niacin. METHODS AND RESULT...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Tuteja, Sony, Qu, Liming, Vujkovic, Marijana, Dunbar, Richard L., Chen, Jinbo, DerOhannessian, Stephanie, Rader, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404865/
https://ncbi.nlm.nih.gov/pubmed/30371334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008461
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