Measuring niacin-associated skin toxicity (NASTy) stigmata along with symptoms to aid development of niacin mimetics

Though cardioprotective, niacin monotherapy is limited by unpleasant cutaneous symptoms mimicking dermatitis: niacin-associated skin toxicity (NASTy). Niacin is prototypical of several emerging drugs suffering off-target rubefacient properties whereby agonizing the GPR109A receptor on cutaneous immu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Dunbar, Richard L., Goel, Harsh, Tuteja, Sony, Song, Wen-Liang, Nathanson, Grace, Babar, Zeeshan, Lalic, Dusanka, Gelfand, Joel M., Rader, Daniel J., Grove, Gary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Methods
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392735/
https://ncbi.nlm.nih.gov/pubmed/28119443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D071696
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi