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Genetic coding variants in the niacin receptor, hydroxyl-carboxylic acid receptor 2 (HCAR2), and response to niacin therapy

OBJECTIVES: Niacin has been used for seven decades to modulate plasma lipids, but its mechanism of action is still unclear. We sought to determine whether variants in the niacin receptor gene, hydroxycarboxylic receptor 2 (HCAR2) are associated with lipid response to treatment. METHODS: Coding varia...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Tuteja, Sony, Wang, Lu, Dunbar, Richard L., Chen, Jinbo, DerOhannessian, Stephanie, Marcovina, Santica M., Elam, Marshall, Lader, Ellis, Rader, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548439/
https://ncbi.nlm.nih.gov/pubmed/28628560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000289
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