Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

BACKGROUND: Niacin is a broad‐spectrum lipid‐modulating drug, but its mechanism of action is unclear. Genome‐wide association studies have identified multiple loci associated with blood lipid levels and lipoprotein (a). It is unknown whether these loci modulate response to niacin. METHODS AND RESULT...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Tuteja, Sony, Qu, Liming, Vujkovic, Marijana, Dunbar, Richard L., Chen, Jinbo, DerOhannessian, Stephanie, Rader, Daniel J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404865/
https://ncbi.nlm.nih.gov/pubmed/30371334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008461
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