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Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

BACKGROUND: Niacin is a broad‐spectrum lipid‐modulating drug, but its mechanism of action is unclear. Genome‐wide association studies have identified multiple loci associated with blood lipid levels and lipoprotein (a). It is unknown whether these loci modulate response to niacin. METHODS AND RESULT...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Tuteja, Sony, Qu, Liming, Vujkovic, Marijana, Dunbar, Richard L., Chen, Jinbo, DerOhannessian, Stephanie, Rader, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404865/
https://ncbi.nlm.nih.gov/pubmed/30371334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008461
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