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Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

BACKGROUND: Niacin is a broad‐spectrum lipid‐modulating drug, but its mechanism of action is unclear. Genome‐wide association studies have identified multiple loci associated with blood lipid levels and lipoprotein (a). It is unknown whether these loci modulate response to niacin. METHODS AND RESULT...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Tuteja, Sony, Qu, Liming, Vujkovic, Marijana, Dunbar, Richard L., Chen, Jinbo, DerOhannessian, Stephanie, Rader, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404865/
https://ncbi.nlm.nih.gov/pubmed/30371334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008461
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