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Binding thermodynamics of metal ions to HIV-1 ribonuclease H domain

Metal-protein interactions are not necessarily tight in many transient biological processes, such as cellular signaling, enzyme regulation, and molecular recognition. Here, we analyzed the binding thermodynamics and characterized the structural effect of divalent metal ions, i.e. Mn(2+), Zn(2+), and...

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Detalhes bibliográficos
Publicado no:J Therm Anal Calorim
Main Authors: Oda, Masayuki, Xi, Zhaoyong, Inaba, Satomi, Slack, Ryan L., Ishima, Rieko
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402781/
https://ncbi.nlm.nih.gov/pubmed/30853849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10973-018-7445-y
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