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Pathological priming causes developmental gene network heterochronicity in autism patient-derived neurons

Autism spectrum disorder (ASD) is thought to emerge during early cortical development. However, the exact developmental stages and associated molecular networks that prime disease propensity are elusive. To profile early neurodevelopmental alterations in ASD with macrocephaly, we monitored patient-d...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Neurosci
Main Authors: Schafer, Simon T., Paquola, Apua C.M., Stern, Shani, Gosselin, David, Ku, Manching, Pena, Monique, Kuret, Thomas J.M., Liyanage, Marvin, Mansour, Abed AlFatah, Jaeger, Baptiste N., Marchetto, Maria C., Glass, Christopher K., Mertens, Jerome, Gage, Fred H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402576/
https://ncbi.nlm.nih.gov/pubmed/30617258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0295-x
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