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Insights into the role of somatic mosaicism in the brain

Somatic mosaicism refers to the fact that cells within an organism have different genomes. It is now clear that somatic mosaicism occurs in all brains and that somatic mutations in a subset of cells can cause various rare neurodevelopmental disorders. However, for most individuals, the extent and co...

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Pubblicato in:Curr Opin Syst Biol
Autori principali: Paquola, Apuã C. M., Erwin, Jennifer A., Gage, Fred H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718369/
https://ncbi.nlm.nih.gov/pubmed/29226270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2016.12.004
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