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The role of somatic mosaicism in brain disease
In this review we discuss the importance of genetic somatic mosaicism and its impact on brain diseases. We start from introducing the different types of somatic mutations, their frequencies and abundances across development and lifespan. We then describe how weakness in DNA repair mechanisms influen...
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| Publicado no: | Curr Opin Genet Dev |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749073/ https://ncbi.nlm.nih.gov/pubmed/32622340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.05.002 |
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