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The role of somatic mosaicism in brain disease
In this review we discuss the importance of genetic somatic mosaicism and its impact on brain diseases. We start from introducing the different types of somatic mutations, their frequencies and abundances across development and lifespan. We then describe how weakness in DNA repair mechanisms influen...
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| Pubblicato in: | Curr Opin Genet Dev |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749073/ https://ncbi.nlm.nih.gov/pubmed/32622340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.05.002 |
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