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Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice

Protection from influenza virus infection is canonically associated with antibodies that neutralize the virus by blocking the interaction between the viral hemagglutinin and host cell receptors. However, protection can also be conferred by other mechanisms, including antibody-mediated effector funct...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Asthagiri Arunkumar, Guha, Ioannou, Andriani, Wohlbold, Teddy John, Meade, Philip, Aslam, Sadaf, Amanat, Fatima, Ayllon, Juan, García-Sastre, Adolfo, Krammer, Florian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401450/
https://ncbi.nlm.nih.gov/pubmed/30626682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01696-18
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