Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model

Seasonal influenza virus epidemics represent a significant public health burden. Approximately 25% of all influenza virus infections are caused by type B viruses, and these infections can be severe, especially in children. Current influenza virus vaccines are an effective prophylaxis against infecti...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Ermler, Megan E., Kirkpatrick, Ericka, Sun, Weina, Hai, Rong, Amanat, Fatima, Chromikova, Veronika, Palese, Peter, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446656/
https://ncbi.nlm.nih.gov/pubmed/28356526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00286-17
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