Influenza A Viruses Expressing Intra- or Intergroup Chimeric Hemagglutinins

A panel of influenza A viruses expressing chimeric hemagglutinins (cHA) with intragroup or intergroup head/stalk combinations was generated. Viruses were characterized for growth kinetics and preservation of stalk epitopes. With a few notable exceptions, cHA viruses behaved similarly to wild-type vi...

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Bibliographic Details
Published in:J Virol
Main Authors: Chen, Chi-Jene, Ermler, Megan E., Tan, Gene S., Krammer, Florian, Palese, Peter, Hai, Rong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794680/
https://ncbi.nlm.nih.gov/pubmed/26764009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03060-15
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